骨川小夫拿出當前暢銷的神秘火車車票炫耀。剛田武、源靜香也想乘火車,懇求小夫也帶他去。這時大雄跑來跟他們說哆啦A夢已經3天都沒回家了,後來大雄只顧找哆啦A夢,大雄和靜香就來去看看,胖虎看「21衛門」戲在房間 ,然後小夫玩宇宙玩具。找到晚上才回家。這時哆啦A夢已經回來了,說他到了22世紀排隊買到銀河列車的車票,可乘搭銀河列車到銀河各個星群遊覽,另一邊神秘的生命體正悄悄來襲……
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